The Importance of Low Temperature Measurement in Pharmaceutical Products
As many of today’s pharmaceutical products are more advanced and complicated, the need to control very
low temperatures has quickly become a requirement.
Historically, most products (many in pill form) had a relatively short shelf life and were typically stored for
short periods of time at refrigeration temperatures. Today, more advanced products are being used that require
longer storage times; and many must be frozen to -70 to -90°C. To protect these products in long-term
storage, reliable systems must be in place to keep the freezing temperatures at the appropriate levels.
The product inside these super freezers can be very expensive. So to avoid product loss and to maximize
quality, having a temperature calibrator that can test these freezers is essential.
Our Solution
The JOFRA RTC-159 Ultra Cooler Temperature Calibrator has a low
range of -100°C, making it the ideal instrument to calibrate the
sensors in super freezers. It features accuracy to 0.06°C, stability
to 0.03°C, and the patented DLC system, which brings unmatched
temperature uniformity in the insert.
Using the autostep feature, the calibrator can be set to test each
point, and then 5°C below and above
the setpoint. This saves the user valuable time and brings consistency
to each calibration.
Your Benefit
In addition to the super-low temperature applications, the RTC-159 can also be used
for many other higher temperature applications in the pharmaceutical industry.
The full range of the RTC-159 is -100°C to 155°C, which allows it to be used to calibrate:
| Super freezers |
-95 to 60°C |
| Freezers |
-60 to 0°C |
| Freeze Drying |
-80 to -60°C |
| Lyophilization |
-50 to 0°C |
| Autoclaves |
110 to 135°C |
| Process Cooling |
-60 to 0°C |
| Dataloggers |
-80 to 150°C |
Every RTC-159 also includes our JOFRACAL calibration software. With JOFRACAL,
RTC calibrators can operate as a stand-alone instrument, using advanced calibration
routines without the assistance of a personal computer. Once all calibrations are
completed, the data can be stored on the user’s computer to provide documentation
of the tests.
Click here for the full application note.